Our research in this area is to identify and tackle the performance issues for a future integrated flow from raw source data to analysis results for Next Generation Sequencing (NGS) analysis pipelines for both DNA and RNA. This research is a key enabler for creating an integrated HPC platform that can be locally deployed in a cut-down form in a current industrial research laboratory, or in future clinical settings for diagnostic purposes on a future commodity small-scale high teraflop/low petaflop cluster. In this instance, we are not just concentrating on performance, but rather usable performance; the flow should incorporate the required level of flexibility for it to be usable in the research lab setting. For this reason the project incorporates the surrounding scripting environment or workflow into the analysis.



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